Kapcsolódó cikkek, videók, képgalériák.
Írj véleményt elsőként! Összefoglaló Pathogen-Derived Immunomodulatory Molecules is a book title hogy a bélférgek may require some explanation.
Microbiology of Eukaryotes Helminths
Pathogens that are present today have evolved following a long association with man and have developed unique strategies that have been optimized by natural selection to subvert the host immunity. As we approach the th anniversary of Charles Darwin's birth, it is appropriate to appreciate that Darwin recognized that pathogens infections play a significant helminths kvíz potent role in natural selection, encompassed by the concept "infection begets natural selection".
This book therefore examines the molecules that pathogens produce, which can modulate or usurp the functions of the immune system. The idea of using molecules from pathogens as a therapeutic is an ancient concept in medicine.
Background We present a study about helminth parasites in wolf Canis lupus signatus from Sierra de la Culebra, a protected area in the Northwest of Spain, where is the largest population of.
Such a strategy is exemplified by vaccination, with pathogen molecules employed to induce protective immunity against the given or related species of pathogen. The following chapters explore the concept of using pathogen-derived immune modulating molecules as a helminths kvíz.
In doing so, they may provide the drug cabinet of the future for treating a spectrum of unrelated disease. Herein, a range of immune modulating molecules or strategies from various pathogens is examined in one volume.
The intention of the book was to have chapters addressing immunomodulating molecules from different pathogens. The range of pathogens considered includes bacteria chapters by Williams, van Strijp and Rooijakkersviruses chapters by Bowie, McFaddenprotozoan parasites Alibertihelminths Harnett, Fallonfungi Sorrell and parasitic ticks Anguita.
Chapters also helminths kvíz specific immunomodulatory molecules or strategies. The diversity of aspects addressed in the book is highlighted by Lucas and colleagues review of the helminths kvíz of viral serine proteinase inhibitors, with a focus on Serp-1, the first new generation of helminths kvíz immunomodulatory molecule currently in clinical trials. While Elliott and Weinstock have contributed helminths kvíz provocative chapter exploring the use of live parasitic helminth infections as a therapeutic strategy for immune-mediated diseases; indeed trials have already been completed for such an approach.
With respect to pathogens usurping an immune pathway, Alcami and colleagues here reviewed the growing number of pathogens that have evolved a range of molecules that can modify many aspects of the chemokine system. This book is timely due to the need to helminths kvíz the horizons of conventional drug discovery. A trend in the biopharmaceutical pipeline of fewer drugs to market is illustrated by USA FDA in approving the lowest number of new molecular entities since As the drug discovery and development industry broadens its search for new drugs to less traditional strategies, this book will be a reference to the potential for exploiting helminths kvíz as a source of the anti-inflammatory drugs of the future.
Finally, this book whets the appetite for the reader, whether in academia or industry, to explore opportunities for exploiting pathogens for the discovery of new processes in immunobiology and, ultimately, for development of new therapies for human inflammatory diseases.